Georg F Vogel Selected Research

Microvillus inclusion disease

1/2022	UNC45A deficiency causes microvillus inclusion disease-like phenotype by impairing myosin VB-dependent apical trafficking.
4/2021	Advanced Microscopy for Liver and Gut Ultrastructural Pathology in Patients with MVID and PFIC Caused by MYO5B Mutations.
11/2015	Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3.
10/2015	An inducible mouse model for microvillus inclusion disease reveals a role for myosin Vb in apical and basolateral trafficking.
7/2014	Loss of syntaxin 3 causes variant microvillus inclusion disease.
1/2014	Microvillus inclusion disease: loss of Myosin vb disrupts intracellular traffic and cell polarity.

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Georg F Vogel Research Topics

Disease

6	Microvillus inclusion disease 01/2022 - 01/2014
5	Diarrhea 02/2024 - 10/2015
2	Liver Diseases (Liver Disease) 02/2024 - 01/2021
2	progressive familial intrahepatic 1 Cholestasis 02/2024 - 12/2022
2	Inflammation (Inflammations) 02/2024 - 12/2022
2	Neoplasms (Cancer) 09/2014 - 01/2014
1	Inborn Urea Cycle Disorders 02/2024
1	Failure to Thrive 02/2024
1	Hyperammonemia 02/2024
1	Ornithine Carbamoyltransferase Deficiency Disease 02/2024
1	Colitis 02/2024
1	Ulcerative Colitis 02/2024
1	Acute Liver Failure (Fulminant Hepatic Failure) 01/2023
1	Aortic Valve Stenosis (Aortic Stenosis) 01/2023
1	Glucose-Galactose Malabsorption 01/2023
1	Biliary Atresia 01/2023
1	End Stage Liver Disease 12/2022
1	Intestinal Diseases (Diseases, Intestinal) 01/2021
1	Hemochromatosis (Bronze Diabetes) 10/2020
1	Atherosclerosis 10/2020
1	Atrophy 01/2017
1	Neoplasm Metastasis (Metastasis) 09/2014
1	Breast Neoplasms (Breast Cancer) 09/2014

Drug/Important Bio-Agent (IBA)

5	Myosins (Myosin)IBA 01/2022 - 01/2014
4	Proteins (Proteins, Gene)FDA Link 04/2021 - 09/2014
2	SodiumIBA 02/2024 - 01/2017
2	Qa-SNARE Proteins (Syntaxin)IBA 11/2015 - 07/2014
1	Ornithine Carbamoyltransferase (Ornithine Transcarbamylase)IBA 02/2024
1	Carbamyl Phosphate (Carbamoyl Phosphate)IBA 02/2024
1	CitrullineIBA 02/2024
1	AmmoniaIBA 02/2024
1	Ligases (Synthetase)IBA 02/2024
1	Phospholipids (Phosphatides)FDA LinkGeneric 02/2024
1	Dextrans (Dextran)FDA Link 02/2024
1	Bile Acids and Salts (Bile Acids)IBA 01/2023
1	Cysteine (L-Cysteine)FDA Link 01/2023
1	Sodium-Glucose Transport ProteinsIBA 01/2023
1	Toll-Like Receptor 3IBA 01/2023
1	LipidsIBA 10/2020
1	Apolipoproteins E (ApoE)IBA 10/2020
1	CholesterolIBA 10/2020
1	IronIBA 10/2020
1	oxidized low density lipoproteinIBA 10/2020
1	LDL CholesterolIBA 10/2020
1	ElectrolytesIBA 10/2020
1	Soluble N-Ethylmaleimide-Sensitive Factor Attachment ProteinsIBA 11/2015
1	Tamoxifen FDA LinkGeneric 10/2015
1	Aprotinin (Trasylol)FDA Link 09/2014
1	Fibrinolysin FDA Link 09/2014
1	Urokinase Plasminogen Activator ReceptorsIBA 09/2014
1	Serine Proteases (Serine Protease)IBA 09/2014
1	InterleukinsIBA 09/2014
1	PlasminogenIBA 09/2014
1	CytokinesIBA 09/2014
1	Peptide Hydrolases (Proteases)FDA Link 09/2014
1	Biomarkers (Surrogate Marker)IBA 01/2014

Therapy/Procedure

4	Liver Transplantation 02/2024 - 12/2022
1	Diet Therapy (Therapy, Diet) 02/2024
1	Parenteral Nutrition 01/2021
1	Transplantation 01/2021